Temas Variados / La Situación Del cáncer Infantil En Uruguay

La Situación Del cáncer Infantil En Uruguay

Composiciones de Colegio: La Situación Del cáncer Infantil En Uruguay
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Enviado por:  asilveira  03 febrero 2014
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Childhood cancer in Uruguay at the beginning of the XXIst century

Silveira A 2,3, Garau M 1,3 , Musetti C 1, Alonso R 1,3, Castillo L 2, Barrios E 1,3

1 National Cancer Registry _CHLCC, Montevideo, Uruguay

2 Centre of Pediatric Hemato-Oncology, Montevideo, Uruguay

3 Department of Quantitative Methods. Faculty of Medicine, Montevideo, Uruguay

Background: Uruguayan Cancer Registry works since 1992 collecting data from the whole country. It has full details of childhood cancer through collaboration with the Center of Pediatric Hemato-Oncology. A report describing incidence and prevalence of childhood malignancies describing 1992-1994 incident cohort was published in 2001. This communication updates figures for the period 1996 to 2010.

Methods: Data from the Uruguayan Cancer Registry regarding incidence and mortality of children (ages 0 to 14) for the period 1995-2010 was analyzed. Age standardized incidence rates (ASIR) and age standardized mortality rates (ASMR) were calculated. Trends were analyzed using Joinpoint Regression method.

Results: Data from 1290 patients were included in the analysis. The overall ASIR was 11.37(girls 10.18, boys 12.52). Age specific rates were higher among children aged 0 to 4 years: 13.13 vs. 10.06 in the 5-9 group and 10.49 in the 10 to 14 group. The most frequent malignancy group was the haematological one 41.9% (leukemia 29.8%, lymphoma 11.9%) followed by central nervous system tumors (18,6%), sarcomas 8,5%. ASMR in this period was 3.71 (M/I ratio 0.33) showing a decrease comparing 1996-2000 (ASMR=4.2) period and 2001-2005(ASMR=3.30), no significant difference was found between 2001-2005 and 2006-2010 (ASMR=3.56) periods. Mortality showed a decreasing but not significant trend (APC=-1.21); that becomes significant when prior years are included in the analysis (1992-2010)

Conclusions: As it has been observed in many countries, cancer incidence in childhood is increasing steadily while mortality shows a significant decre

ase, reaching in 2006-2010 the half that in 1992-1994.

Background.

Uruguay is a country in South America that stretches over 176.215 km2 and has a total population of 3.285.877 inhabitants according to 2011 Census (1). Of these population 696.481 (21.2%) are between 0 to 14 years. The country is divided in 19 regions called Departments; in the capital city Montevideo lives half of the population.

The majority of Uruguayans have Spanish and Italian origins, followed by French, German and others; 87.4% of the population is Caucasian, 9.1% are Afro-descendants and 2.9% others. The male/female ratio is 0.92(1). The levels of demographic variables follow the same tendencies as those observed in developed countries (2). Access to drinking water, education and sewage services is almost universal.

According to 2007 data from the United Nations Program of Development, Uruguay ranked third in Latin America and 50th among 182 countries, with a Human D ...



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